• Methamphetamine

    A Methamphetamine Vaccine?

    Perhaps.

    Three promising formulations could be used in a vaccine to treat methamphetamine addiction, U.S. researchers say.

    Kim Janda of the Scripps Research Institute in La Jolla, Calif., and colleagues note methamphetamine use and addiction cost the United States more than $23 billion annually due to medical and law enforcement expenses, as well as lost productivity.

    The highly addictive crystal meth can cause a variety of problems including cardiovascular damage and death.

    The study, published in the Journal of the American Chemical Society, found three of the new formulations that produced a good immune response in mice were particularly promising.

    Here is the paper.

    Let’s hope for a break through….

  • Methamphetamine

    United Nations Says Methamphetamine Use Surging in Southeast Asia

    Thai Malay Muslim drug users drink 4×100, the popular cheap narcotic drink on September 1, 2011in Narwathiwat, southern Thailand. Translated as ” sii khun roi,” 4 x 100 is a mix of the illegal kratom leaf, cough syrup and Coca-Cola with added ingredients like tranquilizers and marijuana

    Not a good development.

    “Over the past five years, ATS manufacture has spread to new regions which previously reported little or no manufacture,” the UN Office on Drugs and Crime’s 2011 Global ATS Assessment report said.

    “ATS are attractive to millions of drug users in all regions of the world because they are affordable, convenient to the user and often associated with a modern and dynamic lifestyle.”

    The UN’s last assessment on the illicit production and trade in ATS, including ecstasy and methamphetamines, was published in 2008.

    The illicit manufacture of methamphetamines in South-East Asia has continued apace despite a significant rise in seizures from 32 million pills in 2008 to 133 million last year.

    While Myanmar remains the main source of methamphetamine production, new bases have emerged.

    Over the past five years, Indonesia has become a major producer of ecstasy, threatening to replace the Netherlands as the main regional supplier of the up-market party drug.

    In Europe, there is growing evidence of the spread of methamphetamine production replacing less expensive amphetamines.

    Illicit methamphetamine laboratories have been seized for the first time in Austria, Belarus, Lithuania, Poland and Portugal, according to the UN report.

    “In Germany, more methamphetamine laboratories have been reported than amphetamine since 2008,” it said.

    Africa, which appeared to have escaped the ATS menace for years, is now on the map.

    The US government last year indicted members of a large international cocaine trafficking ring for alleged intent to establish a methamphetamine laboratory in Liberia.

    As recently as June, a methamphetamine laboratory was discovered in Nigeria, on the outskirts of Lagos.

    The question remains: Where are they getting the precursor chemicals to manufacture these amphetamine-type stimulants (ATS)? There are only nine manufacturing sites world-wide and can they not be tracked and shut down if they divert the chemicals?

    Somebody is dropping the ball here or intentionally looking the other way.

  • Methamphetamine,  Pseudoephedrine

    Methamphetamine Use Drops Sharply


    Methamphetamine Lab Incidents, 2004-2010

    Great news!

    Close to one in 10 Americans say they regularly use illegal drugs, including cocaine, hallucinogens, heroin, inhalants and prescription drugs used recreationally, according to the National Survey on Drug Use and Health, USA Today reports.The most common drug is marijuana, which has around 17.4 million regular users, or 6.9 percent of the U.S. population. That’s up from the 5.8 percent in 2007. The increase corresponds with the number of states — now at 16 — approving medical marijuana.

    The good news is that use of methamphetamine use, which exploded around the country for the past 10 years, has plummeted. The number of past-month users dropped from 731,000 in 2006 to reach 353,000 last year.

    Since 2001, when methamphetamine began to race around the country, states have restricted or banned ingredients used to make meth, such as the pseudoephedrine often used in over-the-counter cold medications, said Peter Delany, director of the Center for Behavioral Health Statistics and Quality at the Substance Abuse and Mental Health Services Administration.

    “We’ve seen better attention for law enforcement and policy changes. You can’t get all the Sudafed you want anymore,” said Delany.

    And, despite what some cold remedy drug manufacturers say, the new laws both federal and state have been effective.

    The federal government now needs to crack down on the Mexico border, squeeze the Mexican drug cartels that make Meth in Mexico and then smuggle the drug into the USA.

    Here is a video on the Meth Epidemic:

    Watch The Meth Epidemic on PBS. See more from FRONTLINE.

  • Methamphetamine,  Pseudoephedrine

    Oregon’s Law Restricting Pseudoephedrine to Fight Methamphetamine a Success?



    Yes, despite what the drug manufacturers would like to lead you to believe.

    In 2005, Burdick and the three other lawmakers fashioned a law that made Oregon the first state to require a prescription for the purchase of the tablet form of pseudoephedrine … and the state’s drug and crime statistics plummeted.

    Based on the success of the law there, legislators, prosecutors and others are pushing a similar law for Oklahoma, but not everyone in Oregon agrees that all the state’s good news in crime is the result of the pseudoephedrine restriction.

    One statistic that almost everyone credits to the law is that meth labs have essentially disappeared from the state.

    U.S. Drug Enforcement Agency statistics for 2004 show the state had 467 meth lab incidents – including police busts and dumped labs. Last year, there were only nine.

    Several months ago, the Portland Police Department made a meth lab bust and it was remarkable because of its novelty, said Lt. Robert King, spokesman for the Police Department.

    That’s no small accomplishment for the state.

    It means the state hasn’t had meth lab fires that destroy property and people, including innocents.

    It means the state hasn’t had to deal with the toxic sludge left behind by meth cooks.

    It means the state hasn’t had to deal with the expenses of pursuing meth cooks and cleaning up their lab.

    “We didn’t solve the meth problem … but we can honestly say we solved the home meth lab problem,” Burdick said.

    Lincoln County (Ore.) District Attorney Rob Bovett said that alone is a huge accomplishment.
    “Just getting rid of meth labs is vital to public health and safety, (and) drug-endangered children,” he said.

    But as Oregon’s leading evangelist of the pseudoephedrine restriction movement, Bovett is inclined to credit the law with a broader range of accomplishments.

    The website for his Oregon Alliance of Drug Endangered Children, tulsaworld.com/oregonmeth, links the law to fewer meth treatment admissions, fewer meth-related emergency room visits, and the fact that Oregon had the nation’s largest decrease in crime in the nation in 2008 and saw its crime rate at a 50-year low in 2009.

    Oklahomans pushing for the same law here have not been shy about pointing to those statistics in their arguments.

    Read all of the story.

    I think you can agree that this small change in the law requiring prescriptions for pseudoephedrine have made a huge difference in the quality of life for the people in Oregon.

  • Methamphetamine

    Video: Designer Methamphetamine Bath Salts Chemicals Criminalization Bill Passes in New Jersey

    Wow! I had no idea about these drugs – bath salts which mimic the effects of methamphetamine. But, new legislation has passed the New Jersey State Senate to control the chemicals used in “bath salts.”

    New Jersey’s assault on a methamphetamine-style drug known as “bath salts” continued today, as legislation criminalizing six chemicals used to make the powders cleared the state Senate.

    Pamela’s Law — named for a slain Rutgers senior whose alleged killer may have used the powerful stimulants — passed the Senate unanimously. The move is the latest in a flurry of legal action aimed at chasing the dangerous “designer drugs” from the state.

    “The more the truth behind these products masquerading as bath salts comes out, the more banning these powerful chemicals makes sense,” said state Sen. John Girgenti (D-Passaic), one of the bill’s sponsors. “There’s only one reason people purchase these products, and that is to get high.”

    The state Division of Consumer Affairs issued an emergency order banning the six chemicals on April 26. A bill similar to the Senate measure and also called Pamela’s Law, awaits action in an Assembly committee.

    Bath salts, drugs that have nothing to do with bathing but can mimic methamphetamines and cause severe psychotic episodes, made headlines in New Jersey earlier this year when Rutgers senior Pamela Schmidt was killed in the basement of her boyfriend’s Cranford home.

    OK, Congress over to you.

    And, where is the Obama Administration’s DEA in all of this?

    Oh yeah, seizing state’s supplies of sodium thiopental, so they cannot execute murderers.

  • Methamphetamine

    Methamphetamine and Pseudoephedrine: Restrictions on Cold, Allergy Drugs Hurt the Sick?

    Methamorphosis as a result of chronic Methamphetamine abuse

    I want to ask Debra Saunders, really? Unnecessary health costs? Or, is it something else?

    You know the war on drugs has gone too far when politicians keep ratcheting up restrictions on cold and allergy medications in order to prevent kitchen drug labs from buying pills and converting them into methamphetamine.

    In 2005, Congress passed a law requiring consumers to show a driver’s license or other ID in order to purchase Sudafed and 14 other over-the-counter cold and allergy medications. The buyer must register in a logbook.

    Right after the law passed, the amount of methamphetamine that the Drug Enforcement Agency seized dropped, but then it started to rise. The drug trade has proved to be a crafty, adaptable foe. “Mom and pop” meth labs started “smurfing” – sending people to multiple retailers to buy pills. Also, users figured out how to “shake and bake” small quantities of meth in 2-liter jugs. Toxic meth labs found a new home – in cars.

    Worse, Mexican cartels moved in to fill the vacuum. A 2010 U.N. drug report said there had been a sharp decline in the number of small and medium-sized meth labs in the United States, “although production loss was offset by increasing large-scale manufacture in neighboring Mexico.” The report tracked changes in the street price of methamphetamine. Prices spiked for six to nine months after changes in the law, then “manufacturers were able to retool operations and find new sources of chemicals” and the prices dropped back to where they had been.

    Enter state lawmakers. Oregon and Mississippi have already passed laws requiring law-abiding citizens to get prescriptions for what had been over-the-counter medications. Lawmakers in other states – including California, Alabama and Colorado – are considering similar bills.

    I understand that methamphetamine addiction is an ugly creature that destroys families, eats through bodies and endangers children. But if the pharmacy registry and 250-pill per month quantity limit mainly served to drive the trade to Mexico, then the prescription requirement will not stop the trade either.

    Debra, you need more than 250 cold and/or allergy pills per month? If so, you really need to see a physician anyway.

    This whole exercise seems to be an exercise in either unburdening yourself of an inconvenience of a physician’s visit or giving an excuse to the Consumer Healthcare Products association (CHPA) to continue the pseudoephedrine trade in America.

    This commenter to Debra Saunder’s piece more concisely articulates what I am trying to say.

    Folks, what Debra and some of the other making comments are missing is – prescription pseudoephedrine (PSE) is a proven solution for eliminating the domestic poduction of meth – not eliminating meth itself – we have our neighbors to the South to thank for that. Meth labs pose a significant and unique threat that demands immediate attention. Both Oregon and Mississippi have proven Rx PSE works very well. Both states have reduce meth labs seizures 70-90% and equally reduced the number of drug endangered children removed from meth abs each year. The costs to us tax payers associated with meth labs alone is in the billions nationwide (law enforcement, prosecution, incarceration, social services, environmental impact, destroyed homes, etc.). Although Rx PSE won’t eliminate meth coming from Mexico – there is good new there as well. Oregon has actually experienced the greatest reduction in meth crimes, arrests, and people seeking treatment for meth addiction. In Mexico, as mentioned in the article, they are using an old method of making meth that produces meth only half as potent as meth made from PSE. Mexico banned PSE in 2007, as are many other Central and South American countries. And what has been the impact in Oregon, Mississippi and Mexico? No public outcry, no one dying from a running nose, healthcare costs have NOT increased, the price of PSE has not increased, there has not been a run of doc offices or emergency rooms, etc. People making such unsubstantiated claims are speculating or buying the propoganda of Big Pharma who makes a billion dollars each year selling PSE – most of which is being used to make meth – that’s called being in the drug business!

    So, no thanks to your inconvenience, Debra. I really don’t care.

    I do care about Americans becoming addicted to Methamphetamine, committing crimes and the other social costs of this drug.

    You have never treated Meth addicts like I have and the effects are devastating. If you need pseudoephedrine specifically or any other precursor that can be used on the clandestine market to manufacture Meth, get a prescription. By the way, if you need pseudoephedrine in Australia and New Zealand, you must have a Rx.

    It isn’t a lot to ask.

    Here is some information for my readers:

    Oregon and Mississippi require a prescription for the purchase of products containing pseudoephedrine,[31] which has contributed to “the steepest decline in crime rates in the 50 states” in Oregon, and “the number of meth labs in [Mississippi] has fallen by 65 percent.”[32] Oregon also has had tremendous success in reducing the number of methamphetamine lab seizures from 467 in 2004, (the final full year before implementation of the prescription only law),[33] to a new low of 12 in 2009.[34] Some municipalities in Missouri have enacted similar ordinances, including Washington,[35] Union,[36] New Haven,[37] and Cape Girardeau.[38] Certain pharmacies in Terre Haute, Indiana do so as well.[39]

    Another popular approach to controlling the drug on the state level is the use of electronic tracking systems, which require the electronic submission of specified purchaser information by all retailers who sell pseudoephedrine. Several states that have implemented tracking systems are: Tennessee, Kentucky, and Oklahoma.[40] These states have had mixed results in reducing the number of methamphetamine laboratory seizures in their states. Prior to implementation of the system in Tennessee in 2005, methamphetamine laboratory seizures totaled 1,497 in 2004, but were reduced to 955 in 2005, and 589 in 2009.[34] Kentucky’s program was implemented statewide in 2008, but since statewide implementation, the number of laboratory seizures has actually increased.[34] Oklahoma initially experienced success with their tracking system, after implementation in 2006, as the number of seizures of dropped in that year and again 2007, but in 2008 however, seizures began rising again, and have continued to rise in 2009.[34]

    And, here are the requirements of the Combat Methamphetamine Act of 2005 (CMEA):

    Congress passed the Combat Methamphetamine Epidemic Act of 2005 (“CMEA”) as an amendment to the renewal of the USA PATRIOT Act. Signed into law by president George W. Bush on March 6, 2006, the act amended 21 U.S.C. § 830, concerning the sale of pseudoephedrine-containing products. The law mandated two phases, the first needing to be implemented by April 8, 2006 and the second phase to be completed by September 30, 2006. The first phase dealt primarily with implementing the new buying restrictions based on amount, while the second phase encompassed the requirements of storage, employee training, and record keeping.[30] Though the law was mainly directed at pseudoephedrine products it also applies to all over the counter products containing:ephedrine, pseudoephedrine, and phenylpropanolamine, their salts, optical isomers, and salts of optical isomers.[30] Pseudoephedrine was defined as a “scheduled listed chemical product” under 21 U.S.C. § 802(45(A)). The act included the following requirements for merchants (“regulated sellers”) who sell such products:

    • Required a retrievable record of all purchases, identifying the name and address of each party, to be kept for two years
    • Required verification of proof of identity of all purchasers
    • Required protection and disclosure methods in the collection of personal information
    • Required reports to the Attorney General of any suspicious payments or disappearances of the regulated products
    • Required training of employees with regard to the requirements of the CMEA. Retailers must self-certify as to training and compliance.
    • The non-liquid dose form of regulated products may only be sold in unit dose blister packs
    • Regulated products must be stored behind the counter or in a locked cabinet in such a way as to restrict public access
    • Sales limits (per customer):
      • Daily sales limit—must not exceed 3.6 grams of pseudoephedrine base without regard to the number of transactions
      • 30-day (not monthly) sales limit—must not exceed 7.5 grams of pseudoephedrine base if sold by mail order or “mobile retail vendor”
      • 30-day purchase limit—must not exceed 9 grams of pseudoephedrine base. (A misdemeanor possession offense under 21 U.S.C. § 844a for the person who buys it.)

    In regards to the identification that may be used by an individual buying pseudoephedrine products the following constitute acceptable forms of identification:

    • US passport
    • Alien registration or permanent resident card
    • Unexpired foreign passport with temporary I-551 stamp
    • Unexpired Employment Authorization Document
    • Driver’s License or Government issued identification card (including Canadian driver’s license)
    • School ID with picture
    • Voter’s Registration card
    • US Military Card
    • Native American tribal documents

    [30]

    Forty-one states also have laws regulating pseudoephedrine.

    Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Hawai’i (as of May 1, 2009) Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana (as of August 15, 2009) Maryland, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nevada, New Hampshire, New Jersey, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, Rhode Island, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia and Wisconsin have laws requiring pharmacies to sell pseudoephedrine “behind the counter” and to collect personal information from purchasers.

  • Methamphetamine

    CVS Pharmacy Fined $75 Million for Allowing Large Quantities of Pseudoephedrine Sales in Violation of Combat Methamphetamine Epidemic Act



    Come on CVS this is frakking unacceptable and I, for one, will NOT shop at your stores for a while. What don’t you understand about the law?

    CVS Pharmacy Inc. has agreed to pay $75-million in fines for allowing repeated purchases of a key ingredient in the making of methamphetamine in at least five states that also led to a spike in Southern California drug trafficking, authorities said Thursday.

    The largest U.S. operator of retail pharmacies will pay what federal prosecutors said is the largest civil penalty under the Controlled Substances Act.

    The company also will forfeit about $2.6-million in profits earned from the sales of pseudoephedrine, which can often be found in cold medicine and is used to make meth.

    Authorities said CVS didn’t provide enough safeguards to monitor how much pseudoephedrine someone was buying, and the company violated federal drug regulations Arizona, Georgia, California, Nevada, and South Carolina and possibly 20 other states.

    “This case shows what happens when companies fail to follow their ethical and legal responsibilities,” said U.S. Attorney Andre Birotte Jr. “CVS knew it had a duty to prevent methamphetamine trafficking, but it failed to take steps to control the sale of a regulated drug used by methamphetamine cooks as an essential ingredient for their poisonous stew.”

    The company was expected to pay the $75-million fine by Friday. The remaining forfeiture is due within 30 days.

    I mean isn’t this enough incentive to obey the law?

    Methamorphosis as a result of chronic Methamphetamine abuse

    Thanks CVS for turning your back on your American customers.

    Some executive at CVS should be prosecuted criminally for this gross megligence and maybe this will wise up the industry to obey the law.

  • Dentistry,  Methamphetamine

    UCLA School of Dentistry Receives NIH Meth Mouth Research Grant

    Examples of Meth Mouth

    And, there is much more research required to break the cycle of methamphetamine addiction.

    he UCLA School of Dentistry will use a $1.86 million award from the National Institute on Drug Abuse to expand research reported in the Journal of the American Dental Association on the relationship between methamphetamine use and increased dental disease.

    “Given that dental disease is a prominent comorbidity of methamphetamine use, dental professionals are in a unique position to help in the early detection of undisclosed MA use and participate as integral members of a collaborative care team tending to those who use MA,” the UCLA research team said in JADA 2010 Mar; 141(3): 307-318.

    Dr. Vivek Shetty, a professor of oral and maxillofacial surgery and the project’s principal investigator, aims to
    build on research described in JADA as “one of the first systematic investigations of the meth mouth phenomenon.” More information on Methamphetamine Use and Oral Health (Meth Mouth) is available at www.ada.org/goto/meth.

  • Methamphetamine

    Methamphetamine Watch: The U.S. Multilateral Conference Against Methamphetamine

    Image Hosted by ImageShack.us

    From the Unnecessary Epidemic, The Oregonian

    Tomorrow the United States Attorney General and United States Drug Czar will be hosting an important anti-meth conference in America’s heartland.

    Attorney General Michael B. Mukasey and John Walters, the U.S. Drug Czar, will host high-ranking officials from the world’s largest producing and some of the principal consuming nations of methamphetamine and meth precursor chemicals in St. Louis, Missouri on Wednesday, May 7. For the first time, leaders from Mexico, Canada, China, India, and Germany will join federal, state, and local law enforcement professionals from throughout the United States to participate in the National Methamphetamine Chemicals Initiative (NMCI) conference, an initiative of the White House Office of National Drug Control Policy.

    Significant progress has been made against domestic methamphetamine production, trafficking and use over the last several years. Recent changes in the price and purity of meth indicate significant disruptions in the market for the drug. From January to December of 2007, the price per pure gram of meth increased 84 percent, from $152.39 to $280.06, while purity during the same time period decreased 26 percent. Results from workplace drug screenings conducted in 2007 show a more than 50 percent decline in the number of people testing positive for methamphetamine over the past two years.

    But major challenges remain, particularly in the international arena. Many nations lack significant controls to prevent chemical diversion and have yet to comply with their international obligations, although progress has been made in some others. Mexico, for example, has banned all imports of methamphetamine precursors. Attorney General Mukasey and the representatives from Mexico, China, Canada and Germany will sign a Joint Statement on Countering the Diversion of Precursor Chemicals, Synthetic Drugs, and Controlled Pharmaceuticals, calling on all nations to take needed steps to combat this problem and to intensify international cooperation against methamphetamine.

    The United States must make it clear to our allies that either they get a hold on the export of their methamphetamine precursor chemicals or we will interdict their exports and/or sanction their chemical trading with the United States.

    To be blunt – it is time for Mexico and other countries to get their act together or the United States will do if for them.

    Meth Pri_lipstick

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  • Dentistry,  Methamphetamine

    Flap @ California Dental Association Meeting May 3, 2008

    CDA Anaheim Meeting May 1 2008 Part Five 001

    Flap arrived at the Anaheim Hilton and the California Dental Association Convention in record time this morning. The freeways were remarkably clear and the speeding went well @ 75-85.

    Parking in the main lot was easy and smooth. I suspect most everyone will sleep in and crush the place around 10 or so. But, who knows? Maybe the staff and dentists came out yesterday?

    Flap’s complete CDA photo stream on Flickr is here – updated throughout the day.

    My next course will be at 10 AM.

    CDA Anaheim Meeting May 1 2008 Part Five 005

    The class is Crystal Methamphetamine: Your Teeth, Your Health, Your Life presented by Mitchell A. Goodis, D.D.S.

    His website is here: mitchtv.net

    And, here is part one of his video series on You Tube:

    [youtube]http://youtube.com/watch?v=uyS6r7G5dOo[/youtube]

    Meth mouth is real and this is what it looks like. This group of videos is currently used in many schools, police departments, and county support agencies.
    THESE PEOPLE ARE REAL. Most came to our dental office to have teeth extracted, mostly due to use of Crystal Meth. Let’s work together to keep our kids off this devastating and brutal drug.