Senator Edward M Kennedy, 1932-2009

U.S. Senator Edward Kennedy, a towering figure in the Democratic Party who took the helm of one of America’s most fabled political families after two older brothers were assassinated, died at age 77, his family said.

“Edward M. Kennedy, the husband, father, grandfather, brother and uncle we loved so deeply, died late Tuesday night at home in Hyannis Port (Massachusetts),” the Kennedy family said in a statement early on Wednesday.

One of the most influential and longest-serving senators in U.S. history — a liberal standard-bearer who was also known as a consummate congressional dealmaker — Kennedy had been battling brain cancer, which was diagnosed in May 2008.

His death marked the twilight of a political dynasty and dealt a blow to Democrats as they seek to answer President Barack Obama’s call for an overhaul of the healthcare system.

May he rest in peace.